Our neurointerventional surgeons were key contributors to this landmark clinical trial that demonstrated the benefits of endovascular treatment compared to conventional treatment for patients with acute ischemic stroke. The results were published in the New England Journal of Medicine in 2015. The benefits were so significant that the study was halted early because of efficacy. Stroke is a disease that severely impairs functional independence or takes the lives of approximately 60-80% of patients within 90 days after onset. This study demonstrated that rapid endovascular treatment significantly improves functional outcomes and reduces mortality.